منابع مشابه
Serum paraoxonase and arylesterase activities in hemodialysis patients.
Cardiac death from atherosclerosis is common in hemodialysis patients. Human serum paraoxonase (PON1), an esterase, is associated with high-density lipoprotein and inhibits the susceptibility to oxidization of low-density lipoprotein (LDL). The PON1 genetic polymorphisms of 192 Gln/Arg and 55 Leu/Met in the amino acid sequence are partly involved in the PON1 enzyme activity. We investigated the...
متن کاملParaoxonase and Arylesterase Activities in Patients with Cancer
Background: Cancer has the highest disease-related mortality rate in Iran. Reduced activity of paraoxonase reported in patients with cancer may be due to a reduction in its antioxidant properties and a subsequent increased risk of developing cancer. We aimed to assess antioxidant and oxidative status in patients with cancer through measuring the activity of PON1 as an antioxidant enzyme and det...
متن کاملParaoxonase and arylesterase activities in patients with preeclampsia.
OBJECTIVE Paraoxonase is a high density lipoprotein-associated anti-oxidant enzyme. The aim of this study was to investigate the serum paraoxonase and arylesterase activities and associations between these enzymes and lipid hydroperoxide (LOOH) in preeclamptic patients. MATERIALS AND METHODS The study included 47 preeclamptic (25 severe and 22 mild preeclampsia cases) and 20 normotensive heal...
متن کاملPARAOXONASE AND ARYLESTERASE ACTIVITY AMONG HYPERCHOLESTEROLEMIC PATIENTS
Human serum paraoxonase (PON) associated with high density lipoprotein (HDL) , has been postulated to have a role in protecting low-density lipoprotein (LDL) against oxidative damage, which has led to the proposal that PON is an anti-atherogenic and anti-inflammatory enzyme. It has genetic polymorphism at the 191 (R ->Q) and two alloenzymes A and B and three phenotypes A, B, and AB. We exa...
متن کاملParaoxonase-1 and arylesterase activities in patients with colorectal cancer.
BACKGROUND The aim of this study was to evaluate paraoxonase-1 (PON1) and arylesterase (ARE) activities and oxidative stress status in patients with colorectal carcinomas (CRC). MATERIALS AND METHODS Thirty-three patients (20 male, 13 female) with CRC and 30 healthy controls were enrolled in the study. Blood samples were obtained from the CRC patients before adjuvant therapy. Serum samples fr...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2000
ISSN: 1340-3478,1880-3873
DOI: 10.5551/jat1994.7.152