Serum Levels of Insulin-like Growth Factor-I and Insulin-like Growth Factor-I Binding Protein-3: Quality Control for Studies of Stored Serum

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Serum levels of insulin-like growth factor-I and insulin-like growth factor-I binding protein-3: quality control for studies of stored serum.

The insulin-like growth factor (IGF) axis, particularly IGF-I and IGF binding protein-3 (IGFBP-3), has been the subject of much attention because of its role in juvenile growth and their association with cancers at several sites. However, epidemiologic studies of IGF-I and IGFBP-3 have had mixed results and several authors have speculated that quality control (QC), sample storage history, and o...

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Associations of serum carotenoid levels with serum insulin-like growth factor-i and insulin-like growth factor binding protein-3 levels in black men and white men.

Department of Preventive Medicine and Department of Medicine, Feinberg School of Medicine, and Robert H. Lurie Comprehensive Cancer Center, Northwestern University; Department of Pathology, University of Illinois College of Medicine, University of Illinois at Chicago, Chicago, Illinois; Epidemiology and Community Health Division, School of Public Health, and Department of Laboratory Medicine an...

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Maternal serum insulin-like growth factor-I.

The recent report on maternal insulin-like growth factor-I is very interesting. Yang et al. concluded that “maternal serum IGF-I is significantly related to GA, maternal BW, and BMI during pregnancy.” In fact, there are some previous reports on this issue. Pathmaperuma et al. made a completely different observation. In their report, it was reported that serum IGF-I “did not correlate with newbo...

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Serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in children with insulin-dependent diabetes mellitus.

Pubertal development has recently been evaluated from the standpoint of changes in insulin-like growth factor (IGF)-I and IGF-binding protein-3 (IGFBP-3) levels in healthy children. We studied puberty related changes in serum IGF-I and IGFBP-3 levels in 24 patients (11 prepubertal) with insulin dependent diabetes mellitus (IDDM) and 26 healthy subjects (14 prepubertal). Serum IGF-I and IGFBP-3 ...

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Insulin-like growth factor I and insulin-like growth factor binding protein 5 in Crohn's disease.

Insulin-like growth factor (IGF)-I and its binding protein IGF binding protein 5 (IGFBP-5) were highly expressed in inflamed and fibrotic intestine in experimental Crohn's disease. IGF-I induced proliferation and increased collagen synthesis by smooth muscle cells and fibroblasts/myofibroblasts in vitro. Here we studied IGF-I and IGFBP-5 in Crohn's disease tissue. Tissue was collected from pati...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2007

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-07-0044