Serum Levels of 25-Hydroxyvitamin D in Chronic Plaque Psoriasis

Background: Psoriasis is an immune mediated inflammatory disease that involves the innate and acquired arm of immunologic system. The regulatory role for vitamin D in system suggested by presence receptors on activated lymphocytes suppressive or inhibiting effect 1,25-dihydroxyvitamin different autoimmune diseases. Hence, current proposed study aims to 25-hydroxyvitamin status patients with psoriasis.
 Objective: primary objective this was analyze chronic plaque psoriasis comparison healthy control subjects.
 Materials Methods: A comparative cross-sectional study, including forty age- sex-matched subjects, conducted from April 2021 December 2022, at our dermatology department. After informed consent, all were subjected detailed clinical anthropometric examination. Serum concentration evaluated cases subjects. Data be analyzed as per standard statistical protocol.
 Results: mean serum level psoriatic group 18.02 (±SD 9.82) ng/ml 24.47 6.77) ng/ml, respectively. (p=.001) negatively correlated Psoriatic area severity index (PASI) score (r=-.11). However, correlation not significant (p=.493).
 Conclusion: levels significantly lower than