منابع مشابه
Serum LDH and exercise capacity in COPD.
Lactate dehydrogenase (LDH) is the enzyme that catalyses the final step in the glycolytic metabolism, regenerating NAD from reduced NADH, by conversion of pyruvate to lactate. Recently, increased muscle LDH activity has been found in elderly male patients with chronic obstructive pulmonary disease (COPD) who were susceptible to contractile fatigue of the quadriceps femoris muscle following cons...
متن کاملSerum 25-hydroxy vitamin D and exercise capacity in COPD.
Serum 25-hydroxy vitamin D and exercise capacity in COPD Janssens and colleagues have recently reported that vitamin D deficiency is very common in patients affected by chronic obstructive pulmonary disease (COPD) and that vitamin D status correlates with lung function. In the same issue of Thorax, Quint and Wedzicha discuss potential effects of vitamin D deficiency and supplementation in COPD ...
متن کاملHospital admissions and exercise capacity decline in patients with COPD.
Exercise capacity declines with time and is an important determinant of health status and prognosis in patients with chronic obstructive pulmonary disease (COPD). We hypothesised that hospital admissions are associated with exercise capacity decline in these patients. Clinical and functional variables were collected for 342 clinically stable COPD patients. The 6-min walk distance (6MWD) was det...
متن کاملInspiratory capacity-to-total lung capacity ratio and dyspnoea predict exercise capacity decline in COPD.
BACKGROUND AND OBJECTIVE Exercise capacity decline is a predictor of mortality in patients with chronic obstructive pulmonary disease (COPD). Static pulmonary hyperinflation is a key determinant of exercise performance, but its effect on the longitudinal decline in exercise capacity remains unknown. We aimed to study the relationship between the inspiratory capacity-to-total lung capacity (IC/T...
متن کاملEvaluation of COPD progression based on spirometry and exercise capacity.
INTRODUCTION Chronic obstructive pulmonary disease (COPD) is characterized by an airflow limitation that is usually progressive. The progression of COPD expressed as the rate of an annual decline in FEV 1 is very heterogeneous. Exercise capacity in COPD patients is often diminished and becomes worsened over the time. The purpose of the study was to examine how the change in FEV 1 and exercise c...
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ژورنال
عنوان ژورنال: Thorax
سال: 2008
ISSN: 0040-6376
DOI: 10.1136/thx.2007.086363