Serum lactate and lactate dehydrogenase in high concentrations interfere in enzymatic assay of ethylene glycol

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Ethylene glycol poisoning and lactate concentrations.

We were interested to read the article by Manini et al. (1), which confirmed previous observations that a severe ethylene glycol poisoning may lead to falsely elevated lactate levels (2). High lactate levels were indeed measured by enzymatic spectrophotometry (Integra analyzer) but excluded by a specific GC analysis. A linear correlation was nicely demonstrated between the serially determined b...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1996

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/42.9.1489