Serum insulin-like growth factor-I and breast cancer
نویسندگان
چکیده
منابع مشابه
Insulin-like growth factor-I and risk of breast cancer.
Background :-Breast cancer is responsible for the death of millions of women worldwide every year. It is widespread in the world and Iraq that become a genuine problem for public health. The etiology of the disease is unknown. Genetic and hormonal factors are involved in the development of breast cancer and progression of the disease. Insulin like growth factor-ӏ (IGF-ӏ) have been implicated as...
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Targeting hormonal and growth factor signaling pathways has proven to be useful in the treatment of breast cancer. In vitro, animal, and epidemiologic evidence provide a rationale for the relevance of the insulin-like growth factor (IGF) system to breast cancer biology. The IGF system has been implicated in promoting mitogenic, metastatic, and antiapoptotic phenotypes in breast cancer. As a con...
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The recent report on maternal insulin-like growth factor-I is very interesting. Yang et al. concluded that “maternal serum IGF-I is significantly related to GA, maternal BW, and BMI during pregnancy.” In fact, there are some previous reports on this issue. Pathmaperuma et al. made a completely different observation. In their report, it was reported that serum IGF-I “did not correlate with newbo...
متن کاملShort Communication Serum Insulin-Like Growth Factor-I and Platelet-Derived Growth Factor as Biomarkers of Breast Cancer Prognosis
Epidemiologic studies have shown that growth factors and inflammatory mechanisms may affect breast cancer risk and prognosis. The present analysis on 110 postmenopausal breast cancer patients tested if serum insulin-like growth factor I (IGF-I), plateletderived growth factor (PDGF), fructosamine, and C-reactive protein, a serum marker of inflammation, are associated with breast cancer relapse. ...
متن کاملSerum insulin-like growth factor-I and platelet-derived growth factor as biomarkers of breast cancer prognosis.
Epidemiologic studies have shown that growth factors and inflammatory mechanisms may affect breast cancer risk and prognosis. The present analysis on 110 postmenopausal breast cancer patients tested if serum insulin-like growth factor I (IGF-I), platelet-derived growth factor (PDGF), fructosamine, and C-reactive protein, a serum marker of inflammation, are associated with breast cancer relapse....
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2000
ISSN: 0020-7136,1097-0215
DOI: 10.1002/1097-0215(20001201)88:5<828::aid-ijc22>3.0.co;2-8