Serum immunoglobulin response in uncomplicated gonorrhoea.
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چکیده
منابع مشابه
Serum immunoglobulin response in uncomplicated gonorrhoea.
Sera from 225 men and 140 women were examined by an indirect immunofluorescent antibody technique for antibody reactive with Neisseria gonorrhoeae. Antigonococcal IgM was demonstrated at a titre of greater than or equal to 16 in about 45% of infected, but in only 3% of non-infected, patients. Most of this antibody occurred in sera of patients who had been infected for less than 14 days. Antibod...
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Because of the inconvenience of injections and the serious anaphylactic reactions sometimes seen in connection with parenteral penicillin treatment, oral ampicillin has been proposed as an alternative in the treatment of gonorrhoea. Extensive studies have shown that the efficacy of ampicillin in a single dose of 2 g. combined with probenecid, or 2 g. divided into two doses with a 5-hour interva...
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Acrosoxacin was given as a single 300 mg oral dose to 105 patients with acute gonorrhoea. Of the 100 patients followed completely there was a 93% cure rate and 33% of men developed postgonococcal urethritis (PGU). This compared with a 97% cure and 30% PGU with 2 megaunits penicillin. The in vitro activity of acrosoxacin in Nottingham against strains of Neisseria gonorrhoeae showed that it was a...
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A total of 74 men and 26 women with uncomplicated gonorrhoea were treated with ceftizoxime sodium 0.5 g intramuscularly. The cure rate was 99% and included successful treatment of four infections due to beta-lactamase producing organisms. The minimum inhibitory concentrations (MICs) of ceftizoxime in vitro were very much lower than those of penicillin and cefuroxime, and side effects were minim...
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An open study was designed primarily to evaluate the efficacy of rosoxacin in the treatment of gonorrhoea caused by penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG strains. A total of 199 patients (99 men and 100 women) satisfactorily completed follow up examinations, 50 men and 50 women having received rosoxacin 300 mg orally and the remainder having received kanamycin 2 g in...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1979
ISSN: 1368-4973
DOI: 10.1136/sti.55.1.5