SERUM FREE POLYAMINES (SFPA) LEVELS IN CANCER PATIENTS

Serum and urine polyamines in cancer.

Polyamines in serum and urine have been found to be elevated in patients with cancer. A variety of methods employed for these measurements are discussed. Normal values obtained by the most recent methods are presented, and a survey has been made of polyamine levels in cancer patients.

Urinary polyamines in cancer patients.

Polyamines are small hydrocarbon-amine substances which occur ubiquitously in nature (18). Because of their polycationic nature, polyamines have a strong affinity for nucleic acids in vitro, and in vivo studies indicate a possible role for these compounds in the control of rRNA metabolism (2, 4, 8—11, 13). Studies of rapid-growth systems, both normal and neoplastic, indicate that polyamine sy...

Evaluation of serum Amphiregulin levels in breast cancer patients and cancer-free controls

BACKGROUND Expression of the Epidermal Growth Factor Receptor ligand, Amphiregulin, has been associated with estrogen receptor positive breast cancer. As Amphiregulin is proteolytically released from the surface of breast cancer cells, we investigated the levels of Amphiregulin in the serum of breast cancer patients and cancer-free women to evaluate its potential utility as a breast cancer biom...

Serum lipoprotein levels in patients with cancer.

Alterations in serum levels of trace element in patients with breast cancer before and after chemotherapy

Background: Breast cancer is the most common serious disease around the world. The trace elements have a vital role in the metabolism and chemotherapy may change the level of metal ions. Due to the ambiguity of the existence in this regard, the study examined the trace element serum levels in women with breast cancer before and after chemotherapy . Methods: Sixty patients were studied undergoi...