Serum EGF-receptor and HER-2 extracellular domains and prognosis of non-small-cell lung cancer
نویسندگان
چکیده
منابع مشابه
Clinical impact of serum miR-661 in diagnosis and prognosis of non-small cell lung cancer.
OBJECTIVE The aim of this study was to evaluate whether serum miR-661 could serve as a biomarker for the diagnosis and prognosis of non-small cell lung cancer (NSCLC). PATIENTS AND METHODS The expression of serum miR-661 was detected in 150 cases of NSCLC and 114 cases of normal healthy controls by Real-time PCR. Receiver-operating characteristic (ROC) curve analysis was applied to analyze ...
متن کاملLRIG2 expression and prognosis in non-small cell lung cancer
The human leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) protein has been shown to be of prognostic value in several types of human cancer, however, the expression profiles of LRIG2 have not been described in non-small cell lung cancer (NSCLC). The present study evaluated the mRNA expression of LRIG2 in tumor specimens obtained from 39 NSCLC patients by SYBR Green quantitative p...
متن کاملTIMP1 and adverse prognosis in non-small cell lung cancer.
The tumor inhibitor of metalloproteinase (TIMP) family is a natural inhibitor of several matrix metalloproteinase enzymes which are involved in the process of tumor cell invasion through the extracellular matrix. The aim of this study was to examine TIMP1 RNA expression levels in relation to the clinicopathological features in resected primary non-small cell lung cancer (NSCLC). Total cellular ...
متن کاملSerum PTN as an Early Indicator for Diagnosis and Prognosis of Non-Small Cell Lung Cancer
Pleotrophin (PTN), a secretory growth factor, is also known as heparin affinity regulatory peptide (Laaroubi et al., 1995), heparin binding growth associated molecule (Hampton et al., 1992), heparin binding growth factor-8 (Milner et al., 1989), and heprin binding neutrophic factor (Kovesdi et al., 1990), due to its high affinity to heparin. PTN shares 50% homogeneous amino acid sequenc with mi...
متن کاملExpression of Epidermal Growth Factor Receptor and the association with Demographic and Prognostic Factors in Patients with Non-small Cell Lung Cancer
Introduction: Growth, proliferation, survival, and differentiation are the prominent characteristics of cells, which are affected by cancer. Epidermal growth factor receptor (EGFR) plays a pivotal role in the effective control of these features. Given the significance of EGFR signaling pathway in non-small cell lung cancer (NSCLC), EGFR expression is influential on these cell characteristics. I...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2004
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6601987