Serum Dopamine-Beta-Hydroxylase Activity in Endocrine Disease and Hypertension
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چکیده
منابع مشابه
Serum dopamine-beta-hydroxylase activity.
Dopamine-yS-liydroxylase, the enzyme which converts dopamine to norepinephrine, is released into the perfusate upon stimulation of the isolated perfused adrenal gland and after stimulation of the nerves to the isolated perfused spleen. This study was undertaken to determine whether dopamine-/?hydroxylase activity could be detected circulating in blood. By using a sensitive new enzymatic assay, ...
متن کاملPlasma dopamine-beta-hydroxylase activity in oral contraceptive hypertension.
A prospective study was undertaken to evaluate the relative contribution of changes in sympathetic nervous system activity, as reflected by changes in dopamine-beta-hydroxylase (DBH) activity, to the pathogenesis of oral contraceptive-induced hypertension. Precontraceptive and serial post contraceptive determinations of blood pressure, plasma renin activity (PRA), DBH activity, and changes in b...
متن کاملCerebrospinal fluid and plasma dopamine-beta-hydroxylase activity in human hypertension.
Cerebrospinal fluid (CSF) and plasma dopamine-beta-hydroxylase (DBH) activity was measured in 22 normotensive (NT), 31 essential hypertensive (EH), and 11 renal hypertensive (RH) patients. Although no differences were observed in their plasma DBH, the mean CSF-DBH activity and specific activity of EH were significantly lower than those of NT and RH patients. Very low CSF-DBH (less than 0.15 uni...
متن کاملLack of correlation between serum dopamine-beta-hydroxylase activity and blood pressure in middle-aged men.
The activity of serum dopamine-beta-hydroxylase (DBH) was measured in 1194 asymptomatic middle-aged men with diastolic blood pressure ranging from 75 to 125 mm Hg during the baseline examination of a multifactorial intervention program for primary prevention of coronary heart disease. No correlation was present between serum DBH activity and systolic (r = -0.01, NS) or diastolic (r = +0.02, NS)...
متن کاملDopamine beta-hydroxylase deficiency
Dopamine beta-hydroxylase (DbetaH) deficiency is a very rare form of primary autonomic failure characterized by a complete absence of noradrenaline and adrenaline in plasma together with increased dopamine plasma levels. The prevalence of DbetaH deficiency is unknown. Only a limited number of cases with this disease have been reported. DbetaH deficiency is mainly characterized by cardiovascular...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1978
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.54.11_1207