Serum creatine phosphokinase estimations in myocardial infarction.

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Serum creatine phosphokinase estimations in myocardial infarction.

Since the initial report on the clinical value of serum glutamic oxalacetic transaminase (SGOT) determinations in the diagnosis of myocardial infarction (LaDue, Wroblewski, and Karmen, 1954), a considerable amount of work has been done on the blood levels of other enzymes liberated from necrosed heart cells. Because of lack of specificity and difficulty of estimation, very few other enzyme esti...

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Depressed Myocardial Creatine Phosphokinase Activity Following Experimental Myocardial Infarction

Since creatine phosphokinase (CPK) is found predominantly in myocardial and skeletal muscle cells, in contrast to cells participating in the inflammatory response, it was considered likely that measurement of activity of this enzyme in the heart would provide a sensitive and relatively specific index of the extent of ischemic injury following acute coronary artery occlusion. Accordingly, CPK ac...

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Unstimulated whole saliva creatine phosphokinase in acute myocardial infarction.

OBJECTIVE Accurate and rapid diagnosis of acute myocardial infarction (MI) is of major medical and economic importance. The objective of this study was to identify unstimulated whole saliva creatine phosphokinase (CPK) in patients with acute MI. SUBJECTS AND METHODS A case-control study was carried out in 30 normal healthy individuals and 30 patients with acute MI were hospitalized in CCU of ...

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Serial serum creatine phosphokinase MB isoenzyme activity after myocardial infarction. Studies in the baboon and man.

Serum CPK-MB iosenzyme activity was measured serially after mercury embolization of the left circumflex coronary artery in five baboons and after clinical acute myocardial infarction (AMI) in 20 patients. The calculated amount of enzyme released into the baboons' circulation (CPK-MBR) correlated well (r = 0.991) with the amount of MB isoenzyme depleted from the myocardium (CPK-MBD) when a previ...

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Serum Lactic Dehydrogenase Estimations in Myocardial Infarction.

The clinical features presented by coronary occlusion with myocardial infarction are such that, together with electrocardiographic evidence, a correct diagnosis is usually possible (Price, 1950). Electrocardiographic changes, however, may sometimes be delayed, and in about 6 per cent of cases no change is detectable at all (Lancet, 1958). To assist in diagnosing these cases, enzyme tests have b...

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ژورنال

عنوان ژورنال: Heart

سال: 1965

ISSN: 1355-6037

DOI: 10.1136/hrt.27.5.740