Serum biomarker CA 15-3 as predictor of response to antifibrotic treatment and survival in idiopathic pulmonary fibrosis
نویسندگان
چکیده
منابع مشابه
Serum CA 15-3 is increased in pulmonary fibrosis.
BACKGROUND AND AIM OF THE WORK Carbohydrate antigen CA 15-3 is a glycoprotein whose expression, aberrant intracellular localization and changes in glycosylation have been associated with a wide range of cancers. Pulmonary fibrosis represents the final evolution of a chronic inflammation and is defined by the overgrowth of fibroblasts and exaggerated extracellular matrix deposition. The aim of t...
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Idiopathic pulmonary fibrosis (IPF) is the most common of interstitial lung diseases and is characterised by a significant mortality rate. That is way both clinicists and patients are interested to identify factors that may influence outcome of disease. This factors are named biological markers or biomarkers. Their usefulness in diagnostic, monitoring and prognosis of interstitial pneumonia, an...
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ژورنال
عنوان ژورنال: Biomarkers in Medicine
سال: 2020
ISSN: 1752-0363,1752-0371
DOI: 10.2217/bmm-2020-0165