Serum 25-hydroxyvitamin D levels in early and advanced breast cancer

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Serum 25-hydroxyvitamin D levels in early and advanced breast cancer.

BACKGROUND Laboratory and epidemiological studies have implicated vitamin D deficiency in the pathogenesis of breast cancer. 1,25-Dihydroxyvitamin D (1,25(OH)(2)D) promotes differentiation and apoptosis, and potently inhibits proliferation of malignant breast epithelial cells in culture. Serum levels of 1,25(OH)(2)D are higher in normal women than in patients with primary breast cancer. AIM T...

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Low Serum Levels of 25-Hydroxyvitamin D in Association with Type 2 Diabetes in Indian Patients

Objective: Vitamin D deficiency is a common disorder worldwide and is indicated by low serum 25-hydroxyvitamin D levels. Recent studies have suggested an association of 25-hydroxyvitamin D deficiency with diabetes mellitus. The objective of this study is to investigate the relationship between 25-hydroxyvitamin D concentration and type 2 diabetes in South Indian patients. Materials and Methods...

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Mammographic density and serum 25-hydroxyvitamin D levels

BACKGROUND Vitamin D, which influences cellular proliferation and breast tissue characteristics, has been inversely correlated with breast cancer risk. Dietary vitamin D intake has been associated with lower mammographic density (MD), a strong intermediate marker of breast cancer risk. FINDINGS We examined the relationship between MD and serum 25-hydroxyvitamin D [25(OH)D], an integrated meas...

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Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis.

CONTEXT Epidemiological and experimental evidence suggests that high levels of vitamin D, a potent immunomodulator, may decrease the risk of multiple sclerosis. There are no prospective studies addressing this hypothesis. OBJECTIVE To examine whether levels of 25-hydroxyvitamin D are associated with risk of multiple sclerosis. DESIGN, SETTING, AND PARTICIPANTS Prospective, nested case-contr...

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Serum 25-Hydroxyvitamin D Levels in Pediatric Burn Patients

BACKGROUND Previous studies have implicated the important and active role of vitamin D in the immune system. OBJECTIVES The aim of this study was to evaluate serum levels of 25-hydroxyvitamin D in children with burn injuries. MATERIALS AND METHODS In this cross-sectional study, 118 patients with various degrees of burn injuries were enrolled. A checklist consisting of demographic data, tota...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 2006

ISSN: 0021-9746

DOI: 10.1136/jcp.2006.042747