Serotonin transporter polymorphisms and clinical response to sertraline across ethnicities
نویسندگان
چکیده
منابع مشابه
Serotonin transporter polymorphisms predict response inhibition in healthy volunteers
Serotoninergic transmission is reliably implicated in inhibitory control processes. The aim of this study was to test the hypothesis if serotonin transporter polymorphisms mediate inhibitory control in healthy people. 141 healthy subjects, carefully screened for previous and current psychopathology, were genotyped for the 5-HTTLPR and rs25531 polymorphisms. Inhibitory control was ascertained wi...
متن کاملResponse to psychosocial treatment in poststroke depression is associated with serotonin transporter polymorphisms.
BACKGROUND AND PURPOSE The Living Well With Stroke study has demonstrated effectiveness of a brief psychosocial treatment in reducing depressive symptoms after stroke. The purpose of this analysis was to determine whether key variables associated with prevalence of poststroke depression also predicted treatment response. METHODS Response to a brief psychosocial/behavioral intervention for pos...
متن کاملSerotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension.
RATIONALE Serotonin is a pulmonary vasoconstrictor and smooth muscle cell mitogen. The serotonin transporter (SERT) is abundant in pulmonary vascular smooth muscle. Compared with the short (S) allele, the long (L) SERT promoter allele is associated with increased SERT transcription and more severe pulmonary hypertension in a cohort of patients with chronic obstructive pulmonary disease, and was...
متن کاملNeuroticism and polymorphisms in the serotonin transporter gene.
BACKGROUND There is evidence for an association between two different polymorphisms of the human serotonin transporter gene (5-HTT) and the personality trait of neuroticism and affective disorder. METHODS We studied the association between neuroticism and polymorphisms in the 5HTT-linked promoter region and in a variable number tandem repeat region (VNTR) of the 5-HTT gene in 204 people aged ...
متن کاملSerotonin Transporter Gene Polymorphisms and Chronic Illness of Depression
Clinical course of depression is variable. The serotonin transporter gene is one of the most studied genes for depression. We examined the association of serotonin transporter gene polymorphisms with chronicity and recurrent tendency of depression in Korean subjects. This cross-sectional study involved 252 patients with major depression. Patients were genotyped for s/l polymorphisms in 5-HTT pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Progress in Neuro-Psychopharmacology and Biological Psychiatry
سال: 2006
ISSN: 0278-5846
DOI: 10.1016/j.pnpbp.2006.02.015