Serotonin hypothesis and pulmonary artery hypertension
نویسندگان
چکیده
منابع مشابه
Teoria serotoninowa a tętnicze nadciśnienie płucne* Serotonin hypothesis and pulmonary artery hypertension
Tętnicze nadciśnienie płucne jest postępującą chorobą, prowadzącą do niewydolności prawej komory serca i przedwczesnej śmierci. Charakteryzuje się podwyższonym ciśnieniem w tętnicy płucnej, zwiększeniem oporu naczyniowego, przebudową naczyń płucnych oraz dysfunkcją śródbłonka. Patomechanizm tej choroby jest wciąż nieznany. Sugeruje się, że dysfunkcja śródbłonka zaburza równowagę między czynnika...
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Serotonin (5-HT, 5-hydroxytryptamine) has long been recognized as one of the most potent naturally occurring pulmonary vasoconstrictors.1 It was first implicated in the pathogenesis of pulmonary arterial hypertension (PAH) after an outbreak of the disease in Switzerland in the 1960’s among patients taking aminorex fumarate, an appetite suppressant that inhibits serotonin uptake by platelets.2 S...
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Serotonin Signaling in Pulmonary Hypertension Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2006 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.0000225927.04710.33 2006;98:1229-1231 Circ Res. http://circres.ahajournals.org/content/98/10/1229 World ...
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W hile the seminal advance in the treatment of pulmonary artery hypertension (PAH) over the past 2 decades has been pharmacological targeting of dysfunctional endothelium-derived pathways that contribute to the characteristic vascular remodeling of this condition irrespective of etiology (1), several novel interventional techniques have also been useful in selected patients. Atrial septostomy, ...
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A case of pulmonary arterial hypertension in a patient with type-Ia glycogen-storage disease, a rare autosomal recessive disorder caused by a deficiency of glucose-6-phosphatase is reported in this study. It has been suggested that the occurrence of pulmonary arterial hypertension in type-Ia glycogen-storage disease could be due to an abnormal production of vasoconstrictive amines such as serot...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2014
ISSN: 1732-2693
DOI: 10.5604/17322693.1107860