Sero- and apx-typing of German Actinobacillus pleuropneumoniae field isolates from 2010 to 2019 reveals a predominance of serovar 2 with regular apx-profile
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چکیده
منابع مشابه
Production of Apx toxins by field strains of Actinobacillus pleuropneumoniae and Actinobacillus suis.
The three Apx toxins of Actinobacillus pleuropneumoniae have potential value for use in vaccines and diagnostic tests which will be species specific instead of serotype specific, provided that the Apx toxins are species specific and all field strains produce these toxins. We examined 114 A. pleuropneumoniae field strains and found that they secreted either ApxI, ApxII, ApxI and ApxII, or ApxII ...
متن کاملEndobronchial inoculation with Apx toxins of Actinobacillus pleuropneumoniae leads to pleuropneumonia in pigs.
To establish the role of the Apx toxins in the pathogenesis of porcine pleuropneumonia, specific-pathogen-free pigs were inoculated deeply endobronchially with either culture filtrates of Actinobacillus pleuropneumoniae serotype 8 or 9, culture filtrates depleted of the Apx toxins by affinity chromatography, depleted culture filtrate supplemented with purified recombinant Apx toxins (rApx), or ...
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Actinobacillus pleuropneumoniae RTX-toxin III (ApxIII) is implicated as an important virulence factor of A. pleuropneumoniae, the causative agent of porcine pleuropneumonia. Recently, the genes coding for ApxIII (apxIIICA) of serotype 8 were cloned and characterized. The toxin appeared to be a member of the RTX-toxin family, as are the other two secreted toxins of A. pleuropneumoniae, i.e., Apx...
متن کاملPrevalence of serotypes, production of Apx toxins, and antibiotic resistance in strains of Actinobacillus pleuropneumoniae isolated in the Czech Republic
Results of serotyping of 122 strains of Actinobacillus pleuropneumoniae isolated on 21 swine farms in the Czech Republic from January 1999 to December 2000 are presented. The highest prevalence was found for serotype 9 (n = 81, 66.4%), followed by serotype 2 (n = 19, 15.7%). Serotypes 1, 3, 5, 7, 8, 11, and 12 were identified only sporadically. Twenty-six of the isolates were tested for gene-to...
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ژورنال
عنوان ژورنال: Veterinary Research
سال: 2021
ISSN: 1297-9716
DOI: 10.1186/s13567-020-00890-x