Serial Expression Analysis: a web tool for the analysis of serial gene expression data
نویسندگان
چکیده
منابع مشابه
Serial Expression Analysis: a web tool for the analysis of serial gene expression data
Serial transcriptomics experiments investigate the dynamics of gene expression changes associated with a quantitative variable such as time or dosage. The statistical analysis of these data implies the study of global and gene-specific expression trends, the identification of significant serial changes, the comparison of expression profiles and the assessment of transcriptional changes in terms...
متن کاملSerial analysis of gene expression.
The characteristics of an organism are determined by the genes expressed within it. A method was developed, called serial analysis of gene expression (SAGE), that allows the quantitative and simultaneous analysis of a large number of transcripts. To demonstrate this strategy, short diagnostic sequence tags were isolated from pancreas, concatenated, and cloned. Manual sequencing of 1000 tags rev...
متن کاملBayesian Hierarchical Models for Serial Analysis of Gene Expression
In the Serial Analysis of Gene Expression (SAGE) analysis, the statistical procedures have been performed after aggregation of observations from the various libraries for the same class. Most studies have not accounted for the within-class variability. The identification of the differentially expressed genes based on the class separation has not been easy because of heteroscedasticity of librar...
متن کاملSerial analysis of gene expression in a microglial cell line.
We used the serial analysis of gene expression (SAGE) method to systematically analyze transcripts present in a microglial cell line. Over 10,000 SAGE tags were sequenced, and shown to represent 6,013 unique transcripts. Among the diverse transcripts that had not been previously detected in microglia were those for cytokines such as endothelial monocyte-activating polypeptide I (EMAP I), and fo...
متن کاملThe maize root transcriptome by serial analysis of gene expression.
Serial Analysis of Gene Expression was used to define number and relative abundance of transcripts in the root tip of well-watered maize seedlings (Zea mays cv FR697). In total, 161,320 tags represented a minimum of 14,850 genes, based on at least two tags detected per transcript. The root transcriptome has been sampled to an estimated copy number of approximately five transcripts per cell. An ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2010
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkq488