Sequential triage in the first trimester may enhance advanced ultrasound scanning in population screening for trisomy 21
نویسندگان
چکیده
منابع مشابه
Sequential triage in the first trimester may enhance advanced ultrasound scanning in population screening for trisomy 21.
OBJECTIVE To design a trisomy 21 screening protocol for sequential triage in the first trimester, and to evaluate whether it reduces the need for advanced ultrasound scanning to such an extent that this could be dealt with by a limited number of well-trained sonographers only. METHODS Screening results of 31 trisomy 21 affected pregnancies and 16 096 unaffected pregnancies from the first trim...
متن کاملProspective first-trimester screening for trisomy 21 in 30,564 pregnancies.
OBJECTIVE This study was undertaken to evaluate the performance of a 1-stop clinic for first-trimester assessment of risk (OSCAR) for trisomy 21 by a combination of maternal age, fetal nuchal translucency (NT) thickness, and maternal serum-free ss- human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein-A (PAPP-A). STUDY DESIGN OSCAR was carried out in 30,564 pregnancies a...
متن کاملFirst-trimester screening for trisomy 21 using alpha-fetoprotein.
OBJECTIVE To investigate the potential value of adding maternal serum alpha-fetoprotein (AFP) to free β-human chorionic gonadotropin (β-hCG) and PAPP-A and fetal nuchal translucency (NT) thickness in first-trimester screening for trisomy 21. METHODS In this case control study, serum AFP was measured in 100 trisomy 21 and 1,500 euploid pregnancies in which screening for trisomy 21 had been per...
متن کاملFirst-trimester combined screening for trisomy 21 in a predominantly Chinese population.
OBJECTIVE To examine the effectiveness of first-trimester fetal trisomy 21 screening using a combination of maternal age, nuchal translucency thickness (NT) and maternal serum free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A) levels in a predominantly Chinese population in Hong Kong. METHODS This was a prospective study over a 1.5-year period...
متن کاملTwo-stage first-trimester screening for trisomy 21 by ultrasound assessment and biochemical testing.
OBJECTIVES This study was carried out to examine the performance of a contingent policy in first-trimester screening for trisomy 21, in which the estimated risk was first derived by a combination of maternal age, fetal nuchal translucency (NT) thickness, presence/absence of the nasal bone, blood flow in the ductus venosus or flow across the tricuspid valve, and biochemical testing was carried o...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2006
ISSN: 0960-7692,1469-0705
DOI: 10.1002/uog.2780