Sequence Variation intcdAandtcdBof Clostridium difficile: ST37 with TruncatedtcdAIs a Potential Epidemic Strain in China

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Sequence variation in tcdA and tcdB of Clostridium difficile: ST37 with truncated tcdA is a potential epidemic strain in China.

Clostridium difficile is a well-known nosocomial infectious pathogen. Research on C. difficile infection has primarily focused on strains such as the hypervirulent PCR ribotype 027 (sequence type 1 [ST1]) emerging in Europe and North America. However, other new emerging ribotypes in some countries have attracted attention, such as PCR ribotype 17 (ST37) in Asia and Latin America. We collected 7...

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Clostridium difficile infections in China☆

Clostridium difficile (C. difficile) infection has become one of the major hospital-associated infections in Western countries in the last two decades. However, there is limited information on the status of C. difficile infection in Chinese healthcare settings. Given the large and increasing elderly population and the well-recognized problem of over-prescribing of broad spectrum antibiotics in ...

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Draft genome sequence of the nontoxigenic Clostridium difficile strain CD37.

Here we report the draft genome sequence of Clostridium difficile strain CD37, the first nontoxigenic strain sequenced. Every sequenced strain of Clostridium difficile has been shown to contain multiple different mobile genetic elements. The draft genome sequence of strain CD37 reveals the presence of two putative conjugative transposons.

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2014

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.03487-13