Sequence of the chicken GABAAreceptor β3-subunit cDNA

cDNA sequence of an apple ribulose bisphosphate carboxylase small subunit.

Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence.

Transducin, a GTP-binding protein involved in phototransduction in the vertebrate retina, belongs to a family of homologous coupling proteins that also includes Gs and Gi, the regulatory proteins of adenylate cyclase. Here we report the cDNA sequence and deduced amino acid sequence of transducin's alpha subunit (T alpha). The cDNA was isolated, by screening with an antibody probe, from a bovine...

Sequence of a giardin subunit cDNA from Giardia lamblia.

The filamentous protein giardin is structurally associated with microtubules in Giardia lamblia. We present the sequence of one giardin chain (beta-giardin) corresponding to band 14B of Giardia cytoskeleton proteins (1). A Giardia cDNA library cloned and expressed in lamda gt11 was screened with antibodies monospecific to giardin (2). One positive phage clone (SR7) selected for sequencing conta...

cDNA cloning of the chicken DDB1 gene encoding the p127 subunit of damaged DNA-binding protein.

DDB (damaged DNA-binding protein) is a heterodimer, comprised of p48 (DDB2) and p127 (DDB1) subunits, which has a high affinity for a variety of DNA lesions including UV-photoproducts. The mutations in DDB2 gene have been found in a subset of xeroderma pigmentosum complementation group E patients. However, no natural mutation has been identified so far in the cDNA of human DDB1 and the precise ...

Exposure of ligand-binding sites on platelet integrin αIIB/β3 by phosphorylation of the β3 subunit

The exposure of ligand-binding sites for adhesive proteins on platelet integrin α IIB }β $ (glycoprotein IIB}IIIA) by plateletactivating factor (PAF) is transient, whereas sites exposed by αthrombin remain accessible. The same difference is seen in the phosphorylation of the β $ subunit. Inhibition of protein kinases (1 μM staurosporine) and protein kinase C (10 μM bisindolylmaleimide) closes b...