Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus
نویسندگان
چکیده
منابع مشابه
Superovulation and in vitro oocyte maturation in three species of mice (Mus musculus, Mus spretus and Mus spicilegus).
Mouse oocytes can be obtained via superovulation or using in vitro maturation although several factors, including genetic background, may affect response. Our previous studies have identified various mouse species as models to understand the role of sexual selection on the evolution of sperm traits and function. In order to do comparative studies of sperm-oocyte interaction, we sought reliable ...
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Wild populations of the house mouse (Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology. We provide whole genome sequencing data of individuals representing natural populations of M. m. domesticus (24 individuals from 3 populations), M. m. helgolandicus (3 individuals), M. m. musculus (22...
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Here we report the expansion of the genetic code of Mus musculus with various unnatural amino acids including Nɛ-acetyl-lysine. Stable integration of transgenes encoding an engineered Nɛ-acetyl-lysyl-tRNA synthetase (AcKRS)/tRNAPyl pair into the mouse genome enables site-specific incorporation of unnatural amino acids into a target protein in response to the amber codon. We demonstrate temporal...
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INTRODUCTION Electrophoretic techniques by which mixtures of isoenzymes, and homologous proteins generally, may be resolved have become valuable tools in developmental biology. They make possible the study of development at the molecular level, in the sense that the differentiation of protein patterns underlies ontogenetic changes and tissue differences. The greater successes of this approach h...
متن کاملGastrulation in Mus musculus (common house mouse)
As mice embryos develop, they undergo a stage of development called gastrulation [7]. The hallmark of vertebrate gastrulation [7] is the reorganization of the inner cell mass [8] (ICM) into the three germ layers [9]: ectoderm [10], mesoderm [11], and endoderm [12]. Mammalian embryogenesis [13] occurs within organisms; therefore, gastrulation [7] was originally described in species with easily o...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2008
ISSN: 1471-2164
DOI: 10.1186/1471-2164-9-626