Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations
نویسندگان
چکیده
منابع مشابه
Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations
While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood. Here we investigated thermally-activated spontaneous nucleosome sliding mechanisms developing and applying a coarse-grained molecular simulation method that incorporates both long-range electrostatic and shor...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2017
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1005880