Septopreoptic Holoprosencephaly: A Mild Subtype Associated with Midline Craniofacial Anomalies

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Septopreoptic holoprosencephaly: a mild subtype associated with midline craniofacial anomalies.

SUMMARY HPE is a congenital brain malformation characterized by failure of the prosencephalon to divide into 2 hemispheres. We have identified 7 patients who have a mild subtype of HPE in which the midline fusion was restricted to the septal region or preoptic region of the telencephalon. This subtype, which we call septopreoptic HPE, falls in the spectrum of lobar HPE, but lacks significant fr...

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ژورنال

عنوان ژورنال: American Journal of Neuroradiology

سال: 2010

ISSN: 0195-6108,1936-959X

DOI: 10.3174/ajnr.a2123