Sepsis, fluid resuscitation and bedside echocardiography
نویسندگان
چکیده
منابع مشابه
Fluid Resuscitation in Sepsis: Reexamining the Paradigm
Sepsis results in widespread inflammatory responses altering homeostasis. Associated circulatory abnormalities (peripheral vasodilation, intravascular volume depletion, increased cellular metabolism, and myocardial depression) lead to an imbalance between oxygen delivery and demand, triggering end organ injury and failure. Fluid resuscitation is a key part of treatment, but there is little agre...
متن کاملFluid Resuscitation and Markers of Glycocalyx Degradation in Severe Sepsis
Background The aim of this study was to determine the relationship between fluid resuscitation and glycocalyx degradation in severe sepsis. Methodology 15 post-thoracotomy patients with severe sepsis and 11 patients in recovery after open chest surgery (controls) were enrolled. Results Plasma syndecan-1 concentrations were significantly higher in the sepsis group than that in control group,...
متن کاملA critique of fluid bolus resuscitation in severe sepsis
Resuscitation of septic patients by means of one or more fluid boluses is recommended by guidelines from multiple relevant organizations and as a component of surviving sepsis campaigns. The technique is considered a key and life-saving intervention during the initial treatment of severe sepsis in children and adults. Such recommendations, however, are only based on expert opinion and lack adeq...
متن کاملFluid resuscitation in human sepsis: Time to rewrite history?
Fluid resuscitation continues to be recommended as the first-line resuscitative therapy for all patients with severe sepsis and septic shock. The current acceptance of the therapy is based in part on long history and familiarity with its use in the resuscitation of other forms of shock, as well as on an incomplete and incorrect understanding of the pathophysiology of sepsis. Recently, the safet...
متن کاملQuantitative resuscitation in sepsis.
Severe sepsis and septic shock are significant sources of morbidity and mortality in the emergency department (ED), with in-hospital mortality rates from sepsis remaining virtually unchanged between 1970 and 2000. In 2001, Rivers and colleagues demonstrated a 16% absolute reduction in mortality in patients with severe sepsis treated with a protocol-driven resuscitation strategy aimed at hemodyn...
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ژورنال
عنوان ژورنال: QJM: An International Journal of Medicine
سال: 2017
ISSN: 1460-2725,1460-2393
DOI: 10.1093/qjmed/hcx206