Separate roles for Med12 and Wnt signaling in regulation of oxytocin expression
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چکیده
منابع مشابه
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling.
The Mediator complex is commonly seen as a molecular bridge that connects DNA-bound transcription factors to the RNA polymerase II (Pol II) machinery. It is a large complex of 30 subunits that is present in all eukaryotes. The Med12 subunit has been implicated not only in the regulation of Pol II activity, but also in the binding of transcription factors to the bulk of the Mediator complex. We ...
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ژورنال
عنوان ژورنال: Biology Open
سال: 2018
ISSN: 2046-6390
DOI: 10.1242/bio.031229