Sensor-Free Biosensing of Mitral and Aortic Valvular Function During Continuous Flow Left Ventricular Assist Device Support

Continuous flow left ventricular assist devices (CF-LVADs) are miniaturized supporting the failing ventricle and alter blood in cardiovascular system which may cause severe health complications. Regurgitation stenosis mitral aortic valves further aggravate complications limit efficiency of CF-LVAD support. Within this context, real-time monitoring support will allow early detection valve problems timely intervention before valvular worsened. Addressing these issues, study detects regurgitation, stenosis, regurgitation during by electrical current. Patient-specific electrocardiograph RR interval time series with normal sinus rhythm were incorporated into a model including whilst simulating mild moderate regurgitation. Spearman rank test was used to analyze correlation between current signal waveforms over systole atrial contraction. Correlation coefficients signals heart function 0.07 −0.68. Normal 0.82 0.68. 0.86 0.61, respectively. These results suggest that can be for both diagnosis prognosis disorders, thereby representing potential innovation field bioelectronics biosensors.