Selegiline may be toxic in presence of increased dopamine concentrations
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Cytochrome P450 2E1 (CYP2E1) enzyme metabolically activates a large number of low molecular mass xenobiotics probably involved in gastric cancer incidence through activation of procarcinogens. North of Iran is amongst high incidence rate areas of gastric carcinoma where environmental carcinogenic compounds, including agricultural pesticides, are massively used. In this report, we quantitatively...
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Setting 6 sites in the United States; timeframe not specified. Participants Participants were 177 outpatients who met the DSM-IV criteria for major depressive disorder (single episode or recurrent) and had no other primary psychiatric diagnosis. Mean age 42 years (range 20–65); 53% women; 93% white. All participants were free of any psychoactive medications for a minimum of 2 weeks prior to tre...
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ژورنال
عنوان ژورنال: BMJ
سال: 1996
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.312.7032.703b