Selective serotonin reuptake inhibitors: measurement of effect on platelet function

Selective Serotonin Reuptake Inhibitors

It has long been postulated that a deficiency in CNS serotonergic activity is the cause of, or a predisposing factor for, depression. [1] However, the evidence for this association is largely circumstantial and it certainly does not represent an adequate and full model for depression, probably due to there being multiple aetiological factors. [2] Some pharmacological trial data also cast doubt ...

Selective serotonin reuptake inhibitors.

Effect of Donepezil on Cognitive Disorders Due to the Selective Serotonin Reuptake Inhibitors in the Patients with Major Depressive Disorder

Introduction: Many factors cause cognitive impairment, including medication, such as selective serotonine reuptake inhibitor drugs use. On the other hand, many drugs are used in cognitive impairment therapy, including donepezil, which act by inhibiting the cholinesterase enzyme and increase brain acetylcholine. Methods: This study was a double-blind controlled randomized controlled clinical tr...

Treatment of selective mutism: focus on selective serotonin reuptake inhibitors.

Abstract Selective mutism is a pediatric psychiatric disorder that occurs when a child consistently fails to speak in specific situations in which speaking is expected, such as at school and social gatherings, but speaks appropriately in other settings. Selective mutism often is diagnosed when a child starts school and does not talk to teachers or peers, but talks to family members at home; the...

Selective Serotonin Reuptake Inhibitors Effect on Motor Function in Subjects with Parkinson’s Disease and Depression

Depression associated with Parkinson’s disease (PD) is very common and by some estimates, affects 40%-50% of that population. The majority of these patients are treated with a selective serotonin reuptake inhibitor (SSRI). However, extrapyamidal adverse reactions are a side-effect of this medication and by causing inhibition of the dopaminergic path way, these medications could potentially wors...