Selection of a Gentamicin-Resistant Variant Following Polyhexamethylene Biguanide (PHMB) Exposure in Escherichia coli Biofilms
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چکیده
منابع مشابه
Evaluation of polyhexamethylene biguanide (PHMB) as a disinfectant for adenovirus.
IMPORTANCE Swimming pools can be a vector for transmission of adenovirus ocular infections. Polyhexamethylene biguanide (PHMB) is a disinfectant used in swimming pools and hot tubs. OBJECTIVE To determine whether PHMB is an effective disinfectant against ocular adenovirus serotypes at a concentration used to disinfect swimming pools and hot tubs. DESIGN In vitro laboratory study. INTERVEN...
متن کاملBenefit of polyhexamethylene biguanide in Fusarium keratitis.
PURPOSE To report a series of 3 patients with soft contact lens-related Fusarium keratitis. Two of them were treated with the antiamoebic polyhexamethylene biguanide 0.02% (PHMB) in combination with antifungal drugs, and 1 patient was treated with PHMB as sole antifungal regimen. METHODS Chart review of 3 patients treated with PHMB in Fusarium keratitis. Two of them were refractory to the com...
متن کاملEvaluating a dressing impregnated with polyhexamethylene biguanide
Aims: To evaluate a new polyhexamethylene biguanide (PHMB) foam dressing for inclusion in the specialist dressing section of a trust’s wound management formulary. Methods: KendallTM AMD (Covidien) antimicrobial foam dressing’s use was reviewed through a retrospective evaluation of patients who had been treated with the dressing. Data was collected from the medical and nursing notes of 25 patien...
متن کاملPolyhexamethylene biguanide is a relevant sensitizer in wet wipes.
Polyhexamethylene biguanide (PHMB; CAS no. 2875743-3) is a preservative used as a biocide in industrial products (e.g. swimming pool disinfectants), medical devices (e.g. wound cleansers), contact lens solutions, and cosmetics such as wet wipes, deodorants, and facial cleansers. It is considered to be a rare contact allergen, with a sensitization rate of ∼0.5% in an unselected population (1, 2)...
متن کاملStudy of Epigenetic Properties of Poly(HexaMethylene Biguanide) Hydrochloride (PHMB)
Poly(HexaMethylene Biguanide) hydrochloride (PHMB) CAS No. [32289-58-0] is a particularly effective member of the biguanides antiseptic chemical group, and has been in use since the early fifties in numerous applications. It has been proposed that PHMB be classified as a category 3 carcinogen although PHMB is not genotoxic. It has been hypothesized that PHMB may have epigenetic properties effec...
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ژورنال
عنوان ژورنال: Antibiotics
سال: 2021
ISSN: 2079-6382
DOI: 10.3390/antibiotics10050553