Selection for Neuroblastoma Cells that Synthesize Certain Transmitters
نویسندگان
چکیده
منابع مشابه
Selection for neuroblastoma cells that synthesize certain transmitters.
A selection procedure was devised for neurons and related cells that depends upon the ability of the cells to synthesize certain amine neurotransmitters. The rationale for selection is that tyrosine is an essential amino acid for most mammalian cells and that three enzymes from mammalian sources can catalyze the synthesis of tyrosine: phenylalanine hydroxylase (EC 1.14.16.1), tyrosine hydroxyla...
متن کاملPancreatic Beta Cells Synthesize Neuropeptide Y and Can Rapidly Release Peptide Co-Transmitters
BACKGROUND In addition to polypeptide hormones, pancreatic endocrine cells synthesize a variety of bioactive molecules including classical transmitters and neuropeptides. While these co-transmitters are thought to play a role in regulating hormone release little is known about how their secretion is regulated. Here I investigate the synthesis and release of neuropeptide Y from pancreatic beta c...
متن کاملOn certain semigroups of transformations that preserve double direction equivalence
Let TX be the full transformation semigroups on the set X. For an equivalence E on X, let TE(X) = {α ∈ TX : ∀(x, y) ∈ E ⇔ (xα, yα) ∈ E}It is known that TE(X) is a subsemigroup of TX. In this paper, we discussthe Green's *-relations, certain *-ideal and certain Rees quotient semigroup for TE(X).
متن کاملCharacterization of deoxyribozymes that synthesize branched RNA.
We recently reported deoxyribozymes (DNA enzymes) that synthesize 2',5'-branched RNA. The in vitro-selected 9F7 and 9F21 deoxyribozymes mediate reaction of a branch-site adenosine 2'-hydroxyl on one RNA substrate with the 5'-triphosphate of another RNA substrate. Here we characterize these DNA enzymes with respect to their branch-forming activity. Both 9F7 and 9F21 are much more active with Mn(...
متن کاملEx vivo activation of CD56(+) immune cells that eradicate neuroblastoma.
Despite the use of intensive contemporary multimodal therapy, the overall survival of patients with high-risk neuroblastoma is still less than 50%. Therefore, immunotherapy without cross-resistance and overlapping toxicity has been proposed. In this study, we report the development of a novel strategy to specifically activate and expand human CD56(+) (NCAM1) natural killer (NK) immune cells fro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1974
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.71.6.2530