Selectins in cancer immunity
نویسندگان
چکیده
منابع مشابه
Targeting Selectins and Their Ligands in Cancer
Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids has been linked to increased immune cell evasion, drug evasion, drug resistance, tumor invasiveness, and vascular dissemination, leading to metastases. Hypersialylation of cancer cells is largely the result of ...
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Small minerals make strong bones Selectins with a catch ot content simply with a good fit, evolution has apparently designed adhesion molecules that stick optimally only when tugged upon. This property, may stop leukocytes and platelets from lingering in stagnant backwaters in the blood where there is little or no flow. Blood is a medium dominated by flow and shear forces. " If you think flow i...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2018
ISSN: 1460-2423
DOI: 10.1093/glycob/cwx105