Selecting the Right Fractional Flow Reserve in an Unsteady State

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Selecting the Right Fractional Flow Reserve in an Unsteady State: Keep It Simple.

F ractional flow reserve (FFR) works. After 20 years and 3 landmark clinical trials, FFR is arguably the best standard for determining the significance of coronary artery disease. By revealing a specific coronary stenosis’s ischemic potential, FFR often changes clinical decisions on the need for or method of revascularization, leading to demonstrably better clinical outcomes and costeffectivene...

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Impact of Right Atrial Pressure on Fractional Flow Reserve Measurements: Comparison of Fractional Flow Reserve and Myocardial Fractional Flow Reserve in 1,600 Coronary Stenoses.

OBJECTIVES This study sought to assess the impact of a wide range of mean right atrial pressure (Pra) on fractional flow reserve (FFR) measurements. BACKGROUND FFR invasively assesses the ischemic potential of coronary stenoses. FFR is calculated as the ratio of mean distal coronary pressure (Pd) to mean aortic pressure (Pa) during maximal hyperemia. The Pra is considered to have little impac...

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Fractional Flow Reserve

Traditionally, coronary artery disease was assessed using coronary angiographic guidance. Significant lesions were determined by the coronary angiographer. However, interobserver variability showed a significant limitation of interpretation of coronary angiography. Stent deployment and apposition were also evaluated based on angiographic appearance only. Risk factors for stent thrombosis and in...

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Hybrid Instantaneous Wave-Free Ratio–Fractional Flow Reserve versus Fractional Flow Reserve in the Real World

BACKGROUND The instantaneous wave-free ratio (iFR) is a novel method to assess the ischemic potential of coronary artery stenoses. Clinical trial data have shown that iFR has acceptable diagnostic agreement with fractional flow reserve (FFR), the reference standard for the functional assessment of coronary stenoses. This study compares iFR measurements with FFR measurements in a real world, sin...

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Clinical Relevance of Coronary Fractional Flow Reserve: Art-of-state

OBJECTIVE The objective was to delineate the current knowledge of fractional flow reserve (FFR) in terms of definition, features, clinical applications, and pitfalls of measurement of FFR. DATA SOURCES We searched database for primary studies published in English. The database of National Library of Medicine (NLM), MEDLINE, and PubMed up to July 2014 was used to conduct a search using the key...

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ژورنال

عنوان ژورنال: JACC: Cardiovascular Interventions

سال: 2015

ISSN: 1936-8798

DOI: 10.1016/j.jcin.2015.02.019