Seizures and prolonged recovery from general anaesthesia in a horse with guttural pouch mycosis undergoing bilateral arterial coil embolisation

An 11-year-old Holstein mare was referred after profuse bilateral epistaxis due to fungal plaques. Clinical evaluation unremarkable except for mild tachycardia. General anaesthesia induced coil embolisation of the left internal carotid artery, right external and maxillary arteries. Under anaesthesia, cardiorespiratory stability ensured, six coils were deployed under fluoroscopy, whereas three previously found. During recovery from generalised seizures, fast horizontal nystagmus a breath-holding breathing pattern evident. Diazepam medetomidine administered, but seizures resumed shortly after. After administration hypertonic saline solution hydrocortisone, ceased. However, horse remained unresponsive 3 hours despite supportive care consisting oxygen, glucose, fluid therapy warming. Although poor prognosis presumed, recovered one attempt, 180 minutes isoflurane cessation. The present case highlights importance adequate support during anaesthesia.