Segmentation of yeast DNA using hidden Markov models

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چکیده

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Segmentation of yeast DNA using hidden Markov models

MOTIVATION Compositionally homogeneous segments of genomic DNA often correspond to meaningful biological units. Simple sliding window analysis is usually insufficient for compositional segmentation of natural sequences. Hidden Markov models (HMM) with a small number of states are a natural language for description of compositional properties of chromosome-size DNA sequences. RESULTS The algor...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 1999

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/15.12.980