Sedative and Analgesic Effects of Intravenous Midazolam and Ketamine Combination in Bone Marrow Aspiration and Biopsy of Childhood Cancer
نویسندگان
چکیده
Background: Various drugs, including ketamine and midazolam, are used for sedation in children. Objectives: This study aimed to evaluate the effectiveness of intravenous midazolam combination bone marrow aspiration biopsy children with cancer. Methods: descriptive cross-sectional was conducted on 100 aged six months 17 years candidates or biopsy. Sampling easy, accessible, sequential. Children were injected 0.05 mg/kg 1 analgesia. Then, rate, restlessness, nausea, vomiting, laryngospasm, decreased oxygen saturation assessed. Data analyzed using SPSS version 18 software. Results: The mean age 6.8 ± 4.3 years. degree based modified Ramsey score 5.2 0.74. Nausea vomiting observed nine (9%) Six (6%) had arterial less than 90%. Twelve (12%) showed restlessness when waking up. There no cases laryngeal spasms. Conclusions: present that provides suitable analgesia children, low negligible side effects.
منابع مشابه
The Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases
Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
متن کاملComparison effect of Midazolam alone and Midazolam combined with Ketamine in bone marrow aspiration pain in children
Abstract Background This study aimed to compare sedative and analgesic effects of oral Midazolam and Ketamine on Bone Marrow aspiration (BMA) and Lumbar Puncture (LP). Material and Methods This study was a randomized clinical trial and was performed in Amirkola Hospital in north of Iran, Babol during 2011 and 2012 .The study population consisted of 40 patients who underwent the first time of...
متن کاملpatterns and variations in native and non-native interlanguage pragmatic rating: effects of rater training, intercultural proficiency, and self-assessment
although there are studies on pragmatic assessment, to date, literature has been almost silent about native and non-native english raters’ criteria for the assessment of efl learners’ pragmatic performance. focusing on this topic, this study pursued four purposes. the first one was to find criteria for rating the speech acts of apology and refusal in l2 by native and non-native english teachers...
15 صفحه اولGeneral Anesthesia for Lumbar Puncture and Bone Marrow Aspiration /Biopsy in Children with Cancer
Abstract Background Multiple procedures (Lumbar puncture and bone marrow aspiration /biopsy) cause pain, stress, depression and etc for the patients and their families. Various methods have been recommended for pain reduction during invasive procedures. The aim of this study is to report the complications following general anesthesia. Materials and Methods In this prospective observational ...
متن کاملKetamine for bone marrow aspiration and trephine biopsy in children.
To make bone marrow aspiration and trephine biopsy less painful and more acceptable in children a short acting anaesthetic ketamine was used in a dose of 1-2 mg/kg body weight intravenously or 4-5 mg/kg intramuscularly. One hundred cases aged 2 to 13 years were studied. The actual procedure time ranged between 20 seconds and 3 minutes, adequate samples were obtained in 80% of children on first ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Majallah-i ta?q?q?t-i ?ul?m-i pizishk?-i Z?hid?n
سال: 2021
ISSN: ['2008-7977', '2228-6403', '2383-2894']
DOI: https://doi.org/10.5812/zjrms.118151