Secondary metabolites by chemical screening. I. Calcium 3-hydroxyquinoline-2-carboxylate from a streptomyces.
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Secondary metabolites by chemical screening. 4. Detection, isolation and biological activities of chiral synthons from Streptomyces.
by using special staining reagents on TLCshould result in interesting precursors for alkaloid synthesis. The screening was performed by centrifugation of the culture-broth from different Streptomyces strains, adsorption of the compounds in the culture filtrate on Amberlite XAD-16, elution with methanol and concentration. Detection of the amines after TLC separation of the products was done usin...
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Application of a method of chemical screening2*, which based on the prior work of Zahner et al.3\ gave rise to the detection, isolation and structure elucidation of two new angucyclinones4) exhibiting biological activity. In addition, the known compounds 6-deoxy-8-0-methylrabelomycin (3)5'6) and X-14881 E (4)7) were detected in the same culture broth. The producing organism Streptomyces sp. (DS...
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During our search for Streptomyces spp. as new producers of bioactive secondary metabolites, the ethyl acetate extract of the new terrestrial Streptomyces isolate TN262 delivered eight antimicrobially active compounds. They were identified as 1-acetyl-beta-carboline (1), tryptophol (2), cineromycin B (3), 2,3-dihydrocineromycin B (4), cyclo-(tyrosylprolyl) (5), 3-(hydroxyacetyl)-indole (6), bre...
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Actinomycetes were isolated from marine sediment samples collected from the east coast of Chennai, Tamil Nadu, India. Well diffusion and agar plug methods were used for the evaluation of antibiotic production by these isolates against drug resistant Methicillin- resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococci (VRE). The potential isolate VITBRK2 was mass cultured for...
متن کاملSecondary metabolites by chemical screening. 21. Clonostachydiol, a novel anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607).
The producing organism, strain FH-A 6607, was isolated from a soil sample collected near Rantepao, Sulawesi Island (Indonesia) and exhibited a characteristic brown to yellow colored mycelium. The typical conidiophores were found to be in close morphological analogy to gliocladium and are arranged in self-contained long rows (Fig. 1). Combined with further taxonomical investigations the strain F...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1987
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.40.953