Seasonality of Respiratory Syncytial Virus - Lower Respiratory Tract Infection (RSV-LRTI) in Children in Developing Countries

Seasonality of Respiratory Syncytial Virus - Lower Respiratory Tract Infection (RSV-LRTI) in Children in Developing Countries

Lower respiratory tract infection (LRTI) is the leading global cause of death in children between 1 month and 5 years of age [1-4]. Clinical characteristics of RSV infection include upper respiratory infection with rhinorrhea and nasal congestion lasting between 7 and 12 days. Re-infection rates vary between 6% and 83% each year, showing that initial infection does not confer immunity to succee...

RESPIRATORY INFECTION Seasonality of long term wheezing following respiratory syncytial virus lower respiratory tract infection

Background: It is well known that respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) is associated with subsequent wheezing episodes, but the precise natural course of wheezing following RSV LRTI is not known. This study aimed to determine the continuous development of wheezing following RSV LRTI in children up to the age of 3 years. Methods: A prospective cohort study w...

Respiratory Syncytial Virus (RSV) Infection

Seasonality of long term wheezing following respiratory syncytial virus lower respiratory tract infection.

BACKGROUND It is well known that respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) is associated with subsequent wheezing episodes, but the precise natural course of wheezing following RSV LRTI is not known. This study aimed to determine the continuous development of wheezing following RSV LRTI in children up to the age of 3 years. METHODS A prospective cohort study w...

Severity of Respiratory Syncytial Virus Lower Respiratory Tract Infection With Viral Coinfection in HIV-Uninfected Children.

Background Molecular diagnostics enable sensitive detection of respiratory viruses, but their clinical significance remains unclear in pediatric lower respiratory tract infection (LRTI). We aimed to determine whether viral coinfections increased life-threatening disease in a large cohort. Methods Molecular testing was performed for respiratory viruses in nasopharyngeal aspirates collected fro...