“Scrutinize her actions, punish her body to saver her soul”: The Figure of the Governess in Jane Eyre

Why Doesn't Jane Protect Her Privacy?

End-to-end encryption has been heralded by privacy and security researchers as an effective defence against dragnet surveillance, but there is no evidence of widespread end-user uptake. We argue that the non-adoption of end-toend encryption might not be entirely due to usability issues identified by Whitten and Tygar in their seminal paper “Why Johnny Can’t Encrypt”. Our investigation revealed ...

Expression of heregulin, phosphorylated HER-2, HER-3 and HER-4 in HER-2 negative breast cancers.

A significant number of HER-2 amplified breast cancers is effectively treated by trastuzumab and further shows receptor-enhanced chemosensitivity. Recent studies have postulated transactivation of HER-2 also in tumors expressing phosphorylated/activated HER-2 (pHER-2) and of the HER-3/HER-4 ligand heregulin (HRG), independent of HER-2 amplification. As a consequence, a subset of tumors without ...

Preclinical HER-2 Vaccines: From Rodent to Human HER-2

Effective prevention of human cancer with vaccines against viruses, such as HBV and HPV, raises the question whether also non-virus related tumors could be prevented with immunological means. Studies in HER-2-transgenic mice showed that powerful anti-HER-2 vaccines, could almost completely prevent the onset of mammary carcinoma. Protective immune responses were orchestrated by T cells and their...

Advice to the Expectant Mother on the Care of Her Health and That of Her Child

"cortical mosaic" theory of the localization of movements by the unit representation of individual muscles, and stresses the importance, alike to physiologists and clinicians, of a wvider appreciation of the importance of the hypothesis of multiple and overlapping representations of movements rather than muscles. In this admirable essay the author shows himself to share with Hughlings Jackson, ...

Advice to the Expectant Mother on the Care of Her Health and That of Her Child