Screening of herbal plants for inhibitory activity and extracting skin-whitening active ingredients from papaya fruit

Abstract The main theme of this research was to screen for tyrosinase inhibition from extracts seven medicinal plants with the aim applying their skin-whitening compounds cosmetic industry. Specifically, botanical parts include Morus alba L. fruit, Pachyrhizus erosus Glycyrrhiza uralensis F. root, Lonicera japonica T. flower, Chrysanthemum indicum Momordica charantia leaf and Carica papaya which extracted in safe solvents as ethanol water. study results indicated that inhibitory higher ethanol-extracted products. Meanwhile, had high (54.5 ± 2.97%, second only uralensis) widely grown Viet Nam. Hence, fruit pulp chosen suitable extracting conditions. optimal conditions were found, absolute (EtOH) solvent, solid/liquid ratio 1:8 (g/mL), 2 times extraction per patch, each time at 50 °C 30 minutes. expected value yield 22.1%, IC = 768.9 μg/mL, antioxidation (DPPH method) 5 0 1974.5 µg/mL. .