Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms
نویسندگان
چکیده
منابع مشابه
Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms
A population of patients with unexplained neurological symptoms from six major French university hospitals was screened over a 28-month period for primary creatine disorder (PCD). Urine guanidinoacetate (GAA) and creatine:creatinine ratios were measured in a cohort of 6,353 subjects to identify PCD patients and compile their clinical, 1H-MRS, biochemical and molecular data. Six GAMT [N-guanidin...
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A 56-year-old woman with seronegative polyarthritis presented with a four-year history of lower back pain and right-sided sciatica. On examination she had reduced power and impaired sensation in her right leg. Magnetic resonance imaging (MRI) of the spine revealed anterior degenerative slip of L4 on L5 with moderate overall reduction in canal calibre and osteophyte encroachment in the right lat...
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OBJECTIVES To conduct a pilot trial of a primary care Symptoms Clinic for patients with medically unexplained symptoms and evaluate recruitment and retention, and acceptability of the intervention and to estimate potential treatment effects for a full trial. TRIAL DESIGN Randomised parallel group pilot trial. SETTING Primary care in one locality. PARTICIPANTS Primary care database and pos...
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Fourteen common physical symptoms are responsible for almost half of all primary care visits. Only about 10% to 15% of these symptoms are found to be caused by an organic illness over a 1-year period. Patients with medically unexplained symptoms are frequently frustrating to primary care physicians and utilize medical visits and costs disproportionately. This paper will review the relationship ...
متن کاملMedically unexplained symptoms in primary care
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ژورنال
عنوان ژورنال: Orphanet Journal of Rare Diseases
سال: 2012
ISSN: 1750-1172
DOI: 10.1186/1750-1172-7-96