Screening for anti-neoplastic enzymes producing halophilic bacterial extract and their antioxidant activity due to carotenoid synthesis

The methanolic extracts were analyzed for anti-neoplastic enzymes screening, while antioxidant capabilities investigated fifteen isolates. also have enhanced radical scavenging ability against the stable ABTS (2,2’azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (86.34 ± 0.007 mM TE/g extract), nitric oxide (64.79 0.004 μg/ml), phosphomolybdenum (1.69 0.024 mg AAE/g FRAP (ferric reducing of plasma) (28.19 0.012 Fe (II) E/mg) and showed better Ic 50 values on DPPH (2,2-diphenyl-2-picrylhydrazyl) (5.48 mg/ml) assay. Finally, four potent strains from various activities chosen. isolates could synthesize carotenoids that possessed anti-oxidant was identified by UV/Visible spectra, GC–MS LC-MS/MS analysis confirmed isolated had potential to produce compounds might be used primarily as therapeutics. enormous Staphylococcus arlettae , Bacillus subtilis B. tequilensis B . haynesii prevent oxidative-stress-related illnesses like cancer, neurodegeneration, well in food safety markets general. • 1127 halophilic/halotolerant solar salterns India. Twenty-eight halophilic screened enzymes. Many produced more than one type activity. capacity when compared with standards. First study carotenoid production S. tequeilensis reported.