Screening and identification of serum proteomic biomarkers for gastric adenocarcinoma

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Identification of specific biomarkers for gastric adenocarcinoma by ITRAQ proteomic approach

The aim of this study was to identify biomarkers for gastric cancer (GC) by iTRAQ. Using proteins extracted from a panel of 4 pairs of gastric adenocarcinoma samples (stage III-IV, Her-2 negative), we identified 10 up regulated and 9 down regulated proteins in all four pairs of GC samples compared to adjacent normal gastric tissue. The up regulated proteins are mainly involved in cell motility,...

متن کامل

Validation of Serum Biomarkers Derived from Proteomic Analysis for the Early Screening of Preeclampsia

AIM To examine the potential value of previously identified biomarkers using proteomics in early screening for preeclampsia (PE). METHODS 24 blood samples from women who subsequently developed PE and 48 from uncomplicated pregnancies were obtained at 11-13 weeks and analysed after delivery. Cystatin-C, sVCAM-1, and Pappalysin-1 were quantified by ELISA. Maternal characteristics and medical hi...

متن کامل

Identification of Potential Biomarkers for Prostate Cancer in Tears and Serum Using Proteomic Approaches

Jing Jing You, Anna Fitzgerald, Paul J Cozzi, Zhenjun Zhao, Peter Graham, Pamela J Russell, Bradley J Walsh, Mark Willcox, Yong Li University of New South Wales; Minomic Pty Ltd., Australia, Minomic Pty Ltd. Australia, Department of Surgery, St George Hospital, Australia; University of New South Wales, Australia, Institute for Eye Research, Australia; University of New South Wales, Australia, C...

متن کامل

IN TRAOPERATIVE RADIATION THERAPY FOR GASTRIC ADENOCARCINOMA

Intraoperative radiation therapy (IORT) is a multidisciplinary approach in which residual tumors or tumor beds are directly irradiated during a surgical procedure. To evaluate its efficacy, from 1985, we conducted a prospective study including non-metastatic gastric adenocarcinoma treated by surgery, IORT (15 Grays) and postoperative external beam radiotherapy (44 Grays). Up to 1993, 51 ca...

متن کامل

Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Here we show that shotgun and targeted protein sequencing can be used to identify potential prognostic biomarkers in formalin-fixed paraffin-embedded specimens from 9 patients with PDAC with "short" survival (<12 months) and 10 patients with "long" survival (>45 months) undergoing surgical resection. A total of 24 and 14...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2012

ISSN: 1792-0981,1792-1015

DOI: 10.3892/etm.2012.515