Scientists fear new guidelines will stifle basic research
نویسندگان
چکیده
منابع مشابه
Opportunities for basic scientists in disease-oriented research.
Ethanol and signal transduction in the liver. J. B. Hoek, A. P. Thomas, T. A. Rooney, K. Higashi, andE. Rubin Hyaluronan. T. C. Laurent and J. R. E. Fraser Lactate production in adipose tissue: a regulated function with extra-adipose implications. M. DiGirolamo, F. D. Newby, andJ. Lovejoy Dopaminergic mechanisms in the pathogenesis of schizophrenia. M. Goldstein and A. V. Deutch Antibody engine...
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To mimic what happens in actual tumors, researchers utilized a breast cancer cell line that created indolent tumors when xenografted into mice. From the same cell line, they generated a panel of 18 subpopulations, or subclones, by overexpressing in each subclone a different protein linked to cancer progression. They then compared the phenotypic properties of tumors and clonal expansions in two ...
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ژورنال
عنوان ژورنال: Nature
سال: 2001
ISSN: 0028-0836,1476-4687
DOI: 10.1038/35086717