Schistosomiasis Japonica: The DALYs Recaptured

Schistosomiasis Japonica: The DALYs Recaptured

Schistosoma parasites are disease-producing trematodes, or ‘‘blood flukes’’, that infect an estimated 207 million people worldwide [1]. Although schistosomes are common in the developing world, their role in human disease and disability is not widely appreciated, even by tropical medicine and health policy specialists [2]. A disability analysis reported by Finkelstein and colleagues in this edi...

Autoimmunity in schistosomiasis japonica.

Rabbits infected with Schistosoma japonicum either bior monosexually, were clinico-pathologically examined and observed for effects of adreno-cortical hormone on the clinico-pathological findings. Either evaluation or extraction of the fragment of serum protein was performed by electrophoresis on filter paper or starch. Fractions of the serum protein were classified by the difference in specifi...

Experimental cerebral schistosomiasis japonica in primates.

Aspects of the pathogenesis of cerebral schistosomiasis have been elucidated. Arterial embolization alone, by either worms or eggs, does not appear to be likely as a major cause of the disease. When large numbers of eggs enter the brain, sensitization may play a role in the occurrence of neurological signs. These studies support but do not prove the theory that worms in the cerebral veins lay e...

Scintigraphic evaluation of the liver with schistosomiasis japonica.

R-dot-igs Assay for Diagnosing Schistosomiasis Japonica

A fast, specific, sensitive, convenient, and economical rapid-dot-immunogold staining (R-Dot-IGS) assay was used to detect serum antibodies in patients infected with Schistosoma japonicum. The soluble egg antigen of Schistosoma japonicum was added onto microspore membrane. After pre-reacting and blocking, the serum to be detected and sheep anti-human IgG labeled with chloroauric acid were added...