Scavenging Effects of Dexrazoxane on Free Radicals
نویسندگان
چکیده
منابع مشابه
Scavenging Effects of Dexrazoxane on Free Radicals
Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation. However, it is not known whether the antiox...
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Background: Natural medicines have been recently considered more reasonable for human use most notably due to their safety and tolerance. HESA-A is a marine-originated herbal medicine with a variety of healing effects. However, its exact biological mechanism is not clear. The pre-sent study aimed at the evaluation of the HESA-A antioxidant effect. Methods: Chinese hamster ovary (CHO) an...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 2010
ISSN: 1880-5086,0912-0009
DOI: 10.3164/jcbn.10-64