Scalp metastases and scalp cooling for chemotherapy-induced alopecia prevention

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Scalp metastases and scalp cooling for chemotherapy-induced alopecia prevention.

Alopecia is one of the most common adverse events of chemotherapy and although it is not life threatening it can be psychologically devastating. In an effort to reduce chemotherapy-induced hair loss various preventive measurements, such as the scalp cooling technique, tourniquet and medications, have been developed since 1970 [1]. Methods that have been applied in order to induce scalp hypother...

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Reducing chemotherapy-induced alopecia with scalp cooling.

JL The frequency of alopecia varies with different chemotherapy regimens. According to data from Ralph M. Trüeb, MD, alopecia occurs in more than 80% of patients receiving antimicrotubule agents (eg, paclitaxel [Taxol, Bristol-Myers Squibb]), 60–100% of patients receiving topoisomerase inhibitors (eg, doxorubicin), more than 60% of patients receiving alkylators (eg, cyclophosphamide), and 10–50...

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Numerical Simulation of Scalp Cooling to Prevent Chemotherapy–Induced Alopecia

One way of treating cancer is by chemotherapy. Side–effects of chemotherapy include hair loss. Cooling the scalp during treatment can reduce hair loss. For this cooling, a cap containing a cold fluid (cold cap) is used. However, the rate of success of this method varies strongly, because precise mechanisms of preservation are unknown. Temperature and perfusion are thought to play an important r...

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Scalp tourniquets for chemotherapy-induced alopecia.

for five minutes at the time cyclophosphamide (Cytoxan) was injected, seemed promising in preventing hair loss(1,2). The few brief evaluations of scalp tourniquet effectiveness in the literature since then, however, have been highly impressionistic and contradictory(3,4,5,6). Either no controlled studies had been undertaken, or they had not been reported because of the negative results. Two mai...

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Prevention of chemotherapy-induced hair loss by scalp cooling.

BACKGROUND Chemotherapy-induced temporary hair loss is one of the most common and distressing side-effects of cancer therapy. Scalp cooling to reduce this hair loss is a controversial issue for many doctors and nurses. This may be due to inadequate knowledge. METHODS This review from 53 publications and three personal communications focuses on the efficacy of the treatment, side-effects, poss...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2006

ISSN: 0923-7534

DOI: 10.1093/annonc/mdj008