Scaffold Proteins Confer Diverse Regulatory Properties to Protein Kinase Cascades
نویسندگان
چکیده
منابع مشابه
Scaffold proteins confer diverse regulatory properties to protein kinase cascades.
The assembly of multiple signaling proteins into a complex by a scaffold protein guides many cellular decisions. Despite recent advances, the overarching principles that govern scaffold function are not well understood. We carried out a computational study using kinetic Monte Carlo simulations to understand how spatial localization of kinases on a scaffold may regulate signaling under different...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2007
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.21.5.a264