منابع مشابه
Saying yes to exercise and NO to cardiac injury.
Clinical studies demonstrate benefits of exercise in both preventing cardiovascular disease in the general population and mitigating existing disease in cardiovascular patients.1–3 Systemic effects of exercise on skeletal muscle and peripheral vessels as well as metabolism and insulin sensitivity undoubtedly contribute to these benefits. However, growing evidence from animal studies suggests th...
متن کاملSaying no to drugs
Illicit drug use, and the associated health problems, is a frequent issue encountered by medical providers. Because of its salience as a piece of health care information, drug use history is often included in patient charts and presentations by house staff and medical students. However, if used and recorded inappropriately, drug use history can have significant long-lasting effects on the perce...
متن کاملSaying NO to muscular dystrophy
In This Issue In This Issue Saying NO to muscular dystrophy ccording to the prevailing model for Duchenne muscular dystrophy (DMD) pathogenesis, a lack of dystrophin protein makes muscle cells susceptible to mechanical damage, leading to muscle breakdown. On page 123, Wehling et al. suggest that the major damage in DMD may actually be caused by a secondary consequence of dystrophin loss: destru...
متن کاملThirty Years of Saying NO
The historical demonstration by Furchgott and Zawadzki that removal of the endothelium abrogates the in vitro vasodilator effect of acetylcholine has led to the identification 30 years ago of nitric oxide (NO) as a major endogenous local regulator of vascular tone. When the ability of endothelial cells to produce NO is blunted, the ensuing vascular dysfunction sets the stage for the occurrence ...
متن کاملWhen Not Saying NO Does Not Mean Yes: Psychophysiological Factors Involved in Date Rape
To understand how a woman who does not want to be a willing sexual partner can at times acquiesce and not fight the date rape predator, the neurobiology of our responses to threat needs to be understood. Under situations of extreme threat, instead of responding just to danger signals with only the options to fight or flee, we also retain in our nervous system a primitive immobilization response...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2016
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2015.09.073