منابع مشابه
Myelin and saltatory conduction
Essential tutorial on myelin, oligodendrocytes and their functional relevance in the pathophysiology of the brain.
متن کاملSaltatory conduction in unmyelinated axons: clustering of Na+ channels on lipid rafts enables micro-saltatory conduction in C-fibers
THE ACTION POTENTIAL (AP), THE FUNDAMENTAL SIGNAL OF THE NERVOUS SYSTEM, IS CARRIED BY TWO TYPES OF AXONS: unmyelinated and myelinated fibers. In the former the action potential propagates continuously along the axon as established in large-diameter fibers. In the latter axons the AP jumps along the nodes of Ranvier-discrete, anatomically specialized regions which contain very high densities of...
متن کاملTransition to Saltatory Conduction The “Lillie Transition”: Models of the Onset of Saltatory Conduction in Myelinating Axons
Almost 90 years ago, Lillie reported that rapid saltatory conduction arose in an iron wire model of nerve impulse propagation when he covered the wire with insulating sections of glass tubing equivalent to myelinated internodes. This led to his suggestion of a similar mechanism explaining rapid conduction in myelinated nerve. In both their evolution and their development, myelinating axons must...
متن کاملNeurofascins Are Required to Establish Axonal Domains for Saltatory Conduction
Voltage-gated sodium channels are concentrated in myelinated nerves at the nodes of Ranvier flanked by paranodal axoglial junctions. Establishment of these essential nodal and paranodal domains is determined by myelin-forming glia, but the mechanisms are not clear. Here, we show that two isoforms of Neurofascin, Nfasc155 in glia and Nfasc186 in neurons, are required for the assembly of these sp...
متن کاملRunning Head: BIAS AGAINST SALTATORY ALTERNATIONS 1 Evidence for a Learning Bias Against Saltatory Phonological Alternations
This study provides new experimental evidence that people learn phonological alternations in a biased way. Adult participants were exposed to alternations between phonetically dissimilar sounds (i.e., those differing in both voicing and manner, such as [p] and [v]). After learning these alternations, participants assumed, without evidence in the input, that more similar sounds (e.g., [b] and [v...
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ژورنال
عنوان ژورنال: Scholarpedia
سال: 2007
ISSN: 1941-6016
DOI: 10.4249/scholarpedia.3354