Salt-Bridge Energetics in Halophilic Proteins

Salt-Bridge Energetics in Halophilic Proteins

Halophilic proteins have greater abundance of acidic over basic and very low bulky hydrophobic residues. Classical electrostatic stabilization was suggested as the key determinant for halophilic adaptation of protein. However, contribution of specific electrostatic interactions (i.e. salt-bridges) to overall stability of halophilic proteins is yet to be understood. To understand this, we use Ad...

Salt-dependent properties of proteins from extremely halophilic bacteria.

Protective role of salt in catalysis and maintaining structure of halophilic proteins against denaturation

Search for new industrial enzymes having novel properties continues to be a desirable pursuit in enzyme research. The halophilic organisms inhabiting under saline/ hypersaline conditions are considered as promising source of useful enzymes. Their enzymes are structurally adapted to perform efficient catalysis under saline environment wherein n0n-halophilic enzymes often lose their structure and...

Molecular Adaptation of Halophilic Proteins

Simple Method for Killing Halophilic Bacteria in Contaminated Solar Salt.

Adding acid to brines or mixing acid phosphate with the salt used in preserving fish was recommended by Gibbons (Progr. Rep. Atlantic Fish. Exp. Sta., no. 14, p. 13, 1935), because it was observed that under acid conditions the halophilic bacteria that spoil salted fish cannot grow. The red halophile, Halobacterium cutirubrum, was found to be extremely sensitive to pH changes (Kushner and Bayle...